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A novel herbal drug delivery system for bioavailability enhancement: A literature review Advance Pharmaceutical Journal

Review Articles

2025  |  Vol: 10(3)  |  Issue: 3(May-June) | https://doi.org/10.31024/apj.2025.10.3.3
A novel herbal drug delivery system for bioavailability enhancement: A literature review

Manish Kumar, Deepanshu Shukla, P. K. Jain*, Nakul Gupta

IIMT College of Pharmacy, Greater Noida, U.P.

*Address for Corresponding Author

Dr. P.K. Jain

IIMT College of Pharmacy, Greater Noida, U.P.


Abstract

Herbal medicine has been an integral part of traditional healthcare systems for centuries. However, the efficacy of herbal drugs is often hindered by poor solubility, stability, and bioavailability. Advanced drug delivery systems offer innovative solutions to these limitations by improving drug absorption, targeted delivery, and therapeutic efficacy. This review explores the transition from conventional herbal formulations to novel drug delivery systems, highlighting the latest advancements in the field. Conventional herbal drug delivery methods, such as decoctions, tinctures, and powders, have significant drawbacks, including inconsistent bioavailability and degradation of active compounds. To address these challenges, modern drug delivery technologies, such as nanoparticles, liposomes, phytosomes, ethosomes, niosomes, and transferosomes, have been developed. These novel formulations enhance the stability and bioavailability of herbal compounds, ensuring better therapeutic outcomes. Additionally, hydrogels and biodegradable polymers have emerged as promising carriers for controlled and sustained herbal drug release. The integration of herbal drug delivery into modern medicine has shown promising results in cancer therapy, neurological disorders, cardiovascular diseases, and antimicrobial treatments. These advancements have opened new avenues for the application of herbal medicine in contemporary healthcare.

Keywords: Herbal drug delivery, bioavailability, nanoparticles, liposomes, phytosomes, transferosomes, nanotechnology, controlled drug release

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