Research Articles

2023  |  Vol: 8(3)  |  Issue: 3(May-June) | https://doi.org/10.31024/apj.2023.8.3.1

Volatile constituents and anti-inflammatory activity of the essential oil from the seeds and pulp of Syzygium zeylanicum (L.) DC.

Shilpa.K J^1#., Krishnakumar G¹., Chandrashekhar G. Joshi²., Karunakar Hegde³ 

¹Department of Applied Botany, Mangalore University, Mangalagangothri - 574199, Mangalore, Karnataka, INDIA

²Department of Biochemistry, Mangalore University, Mangalagangothri - 574199, Mangalore, Karnataka, INDIA

³Department of Pharmacology, Srinivas College of Pharmacy, Valachil, 574143, Mangalore, Karnataka, INDIA

^#Address for Corresponding Author

Dr. Shilpa K. J.

Department of Applied Botany, Mangalore University, Mangalagangothri - 574199, Mangalore, Karnataka, INDIA

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Abstract

Syzygium zeylanicum, yields edible fruits and fresh leaves and the plant parts have essential oil. The seed and the fruit pulp were subjected to GC–MS. The seed essential oil was examined for anti-inflammatory activity. The seed and the fruit pulp yielded 1.25 % and 0.5 % colourless essential oil on dry weight basis respectively. The seed essential oil was rich in monoterpene hydrocarbons accounting for 80.26 %, out of which α–pinene alone constituted 60.99 %. Thirty five compounds representing 84.81 % were characterized in the pulp with α – caryophyllene (15.11 %), α–pinene (9.54 %), α–beta–trans–Ocimene (8.10 %), Trans (Beta) – Caryophyllene (7.62 %), Humulene Oxide (7.28 %), Cymene (6.38 %), Phellandrene (5.96 %), Caryophyllene oxide (5.05%) as major compounds. The oil exhibited dose dependent significant anti-inflammatory activity in experimental rats. The essential oil can be further exploited for various pharmaceutical purposes.

Keywords: GC-MS, α–pinene, anti-inflammatory, Syzygium zeylanicum, Essential oil, Carageenan